Association between left ventricular diastolic function and blood pressure variability in essential hypertensive patients / 中华心血管病杂志
Chinese Journal of Cardiology
;
(12): 683-686, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-261507
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the relationship between blood pressure variability (BPV) and left ventricular diastolic function in patients with essential hypertension.</p><p><b>METHODS</b>Left ventricular diastolic function of 252 hypertensive patients were assessed by early (E) diastolic transmitral flows to early diastolic mitral annular velocity (Ea) (E/Ea) ratio derived from Doppler echocardiography. Patients were divided into two groups according to normal left ventricular diastolic function group (E/Ea<15, n = 168) and left ventricular diastolic dysfunction group (E/Ea ≥ 15, n = 84). All patients were monitored by ambulatory blood pressure. Standard deviation (SD) and coefficient of variation (CV) of blood pressure were calculated as the BPV. Relationship between BPV and left ventricular diastolic function were analyzed by multivariate logistic regression analysis.</p><p><b>RESULTS</b>All-day average diastolic blood pressure(DBP), the day systolic blood pressure (SBP), night SBP, night DBP, SBPSD, DBPSD and DBPCV in the left ventricular diastolic dysfunction group were significantly higher than in the normal diastolic function group (all P < 0.05). Multivariate logistic regression analysis showed that left ventricular diastolic dysfunction was associated with SBPSD (OR1.126, 95%CI1.054-1.203, P < 0.01), SBPCV (OR1.127, 95%CI1.036-1.225, P < 0.01) in this patient cohort.</p><p><b>CONCLUSION</b>High variability of SBP is correlated with left ventricular diastolic dysfunction in hypertensive patients.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Physiology
/
Blood Pressure
/
Logistic Models
/
Ventricular Function, Left
/
Diastole
/
Essential Hypertension
/
Hypertension
Type of study:
Risk factors
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Cardiology
Year:
2013
Type:
Article
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