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Correlation between typing of peripheral neuroblastic tumors and prognosis: a clinicopathologic study of 135 cases / 中华病理学杂志
Chinese Journal of Pathology ; (12): 151-155, 2011.
Article in Chinese | WPRIM | ID: wpr-261839
ABSTRACT
<p><b>OBJECTIVE</b>To study the clinicopathologic characteristics of peripheral neuroblastic tumors and to investigate the prognostic significance of International Neuroblastoma Pathology Classification (INPC).</p><p><b>METHODS</b>One hundred and thirty-five cases of peripheral neuroblastic tumors encountered in Shanghai Children's Medical Center were enrolled into the study. All the cases were classified according to INPC and International Neuroblastoma Staging System (INSS). The follow-up data were analyzed.</p><p><b>RESULTS</b>The consensus diagnoses of the 135 cases were as follows 80 cases (59.2%) of neuroblastoma, 24 cases (17.8%) of ganglioneuroblastoma, intermixed, 17 cases (12.6%) of ganglioneuroma and 14 cases (10.4%) of ganglioneuroblastoma, nodular. The cases were subdivided into 2 subgroups favorable histology (number = 90, 66.7%) and unfavorable histology (number = 45, 33.3%). According to INSS, the number of cases in stages I, II, III and IV was 22 (16.3%), 24 (17.8%), 34 (25.2%) and 55 (40.7%), respectively. The survival of peripheral neuroblastic tumors correlated with histologic diagnosis, INPC and INSS (P < 0.05).</p><p><b>CONCLUSION</b>Diagnostic categorization of peripheral neuroblastic tumors according to INPC is of prognostic value.</p>
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Pathology / Peripheral Nervous System Neoplasms / General Surgery / Survival Rate / Retrospective Studies / Follow-Up Studies / Classification / Ganglioneuroblastoma / Ganglioneuroma / Neoplasm Staging Type of study: Observational study / Prognostic study Limits: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male / Infant, Newborn Language: Chinese Journal: Chinese Journal of Pathology Year: 2011 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pathology / Peripheral Nervous System Neoplasms / General Surgery / Survival Rate / Retrospective Studies / Follow-Up Studies / Classification / Ganglioneuroblastoma / Ganglioneuroma / Neoplasm Staging Type of study: Observational study / Prognostic study Limits: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male / Infant, Newborn Language: Chinese Journal: Chinese Journal of Pathology Year: 2011 Type: Article