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Endophytic fungi from Ginkgo biloba and their biological activities / 中国中药杂志
China Journal of Chinese Materia Medica ; (24): 2133-2137, 2010.
Article in Chinese | WPRIM | ID: wpr-262207
ABSTRACT
<p><b>OBJECTIVE</b>To research the isolation method, identification and screen for bioactivities endophytic fungi from ginkgo.</p><p><b>METHOD</b>Endophytic fungi from ginkgo were separated. By means of microdilution method, activities of endophytes against pathogenic fungi were tested. Then, using DPPH, the antioxidant activities were measured.</p><p><b>RESULT</b>Nine strains (16.1%) showed antifungal activities against Candida albicans, Cryptococcus neoformans, Trichophyton rubrum and Aspergillus fumigatus. Among these bioactive strains, the growth of T. rubrum was strongly inhibited by T-1-2-1, as the MIC80 was equal to fluconazole, the positive control. Five strains (8.9%) showed antioxidant activities. Among them sample T-3-2-2 and T-6-5-7 showed the strongest antioxidant activities.</p><p><b>CONCLUSION</b>Endophytic fungi of ginkgo would be potential and rich resources for drug development.</p>
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Pharmacology / Aspergillus fumigatus / Trichophyton / Candida albicans / Microbial Sensitivity Tests / Fluconazole / Chemistry / Ginkgo biloba / Cryptococcus neoformans / Fungi Language: Chinese Journal: China Journal of Chinese Materia Medica Year: 2010 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pharmacology / Aspergillus fumigatus / Trichophyton / Candida albicans / Microbial Sensitivity Tests / Fluconazole / Chemistry / Ginkgo biloba / Cryptococcus neoformans / Fungi Language: Chinese Journal: China Journal of Chinese Materia Medica Year: 2010 Type: Article