McCune-Albright syndrome: a difficult and complicated case study / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 311-314, 2006.
Article
in Chinese
| WPRIM
| ID: wpr-262708
ABSTRACT
McCune-Albright syndrome is a rare G proteins alpha disorder. The disorder is characterized by polyostotic fibrous dysplasia, sexual precocity and hyperpigmented macules. It is caused due to mutations in the gene Gsalpha that incodes the alpha subunit of the trimeric guanosine triphate-binding protein. There is no specific treatment for this syndrome. Treatment is generally symptomatic. This paper reported three cases of McCune-Albright syndrome and reviewed the relevant literatures regarding to the pathogenesis, pathological features, diagnosis and treatment. All three cases presented with a characteristic triad polyostotic fibrous dysplasia, sexual precocity and hyperpigmented macules and were thus definitely diagnosed with McCune-Albright syndrome.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Prognosis
/
Therapeutics
/
Diagnosis
/
Diagnosis, Differential
/
Fibrous Dysplasia, Polyostotic
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Child
/
Child, preschool
/
Female
/
Humans
Language:
Chinese
Journal:
Chinese Journal of Contemporary Pediatrics
Year:
2006
Type:
Article
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