Endoscopic surgery in occupation lesions of the skull base / 中华耳鼻咽喉头颈外科杂志

ABSTRACT

<p><b>OBJECTIVE</b>To explore the application of endoscopic endonasal approach in surgery for occupation lesions of the skull base.</p><p><b>METHODS</b>Forty-two cases of skull base lesions treated by endoscopic endonasal surgery were analyzed retrospectively. There were 13 malignant tumors in anterior or middle cranial fossa, 8 chordoma, 5 invasive pituitary adenoma, 4 fibrous dysplasia of the sphenoid bone, 3 neurofibroma, 3 fibroangioma, 3 ossifying fibroma and 3 other lesions.</p><p><b>RESULTS</b>Lesions were removed completely in 36 patients, 2 of them were performed in two stages because of sever bleeding, and subtotally in 6 patients. The complications included 1 acroisa of right eye and 1 cerebrospinal fluid otorrhea. Follow-up ranged 6 to 81 months after the surgery. Five patents were lost of follow-up. Eight patients recurred and 6 patients died.</p><p><b>CONCLUSIONS</b>The endoscopic transnasal surgery is a safe, effective and minimally invasive approach to resect skull base lesions in condition of indications, surgeon's experience and the facilities.</p>