Flavones from Helichrysi flos syn / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the chemical constituents of Helichrysi flos syn.</p><p><b>METHOD</b>The chemical constituents were isolated by various methods of isolation (silica gel, ODS column chromatography and HPLC) and their structure were elucidated by the analysis of spectral data and chemical properties.</p><p><b>RESULT</b>Seven flavone compounds were isolated from the MeOH extract of Helichrysi flos syn. The chemical structures were elucidated as quercetin-3-O-beta-D-glucopyranoside (1), apigenin-7-O-beta-D-gentiobioside (2), quercetin-3-O-rutinoside (3), apigenin-7,4'-di-O-beta-D-glucopyranoside (4), kaempferol-3,4'-di-O-beta-D-glucopyranoside (5), quercetin-3,3'-di-O-beta-D-glucopyranoside (6), apigenin-7-O-beta-D-glucopyranosiduronic acid methyl ester (7).</p><p><b>CONCLUSION</b>Compounds 2, 4-7 were obtained from the genus Helichrysum for the first time.</p>