Clinical analysis of invasive fungal infections in patients with hematologic malignancies / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 492-495, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-263365
ABSTRACT
The aim of this study was to investigate the clinical situation of invasive fungal infections in patients with hematological malignancies, and discuss the susceptible factors and precautions. 541 patients with hematological malignancies from 2008 Jan to 2011 Dec in hospital 307 of Chinese PLA were statistically retrospectively analyzed in term of clinical manifestation, image examination, culture results of secretions, therapy and so on. The results showed that 63 out of 541 patients got invasive fungal infections. The respiratory tract and intestinal tract were the most common infection sites (62.34 and 19.48, respectively); Candida albicans (66.67) and Candida glabrata (12.82) were the most common pathogens. It is concluded that the main risk factors are as follows primary diseases, chemotherapy, glucocorticoid, leukopenia after chemotherapy, applications of broad-spectrum antibiotics and aging. It is suggested that a stratification of risk factors is helpful in preventing and treating invasive fungal infections.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Virulence
/
Candida
/
Cross Infection
/
Retrospective Studies
/
Hematologic Neoplasms
/
Microbiology
/
Mycoses
Type of study:
Observational study
/
Risk factors
Limits:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Child
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Experimental Hematology
Year:
2012
Type:
Article
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