The relationship between lymphangiogenesis and cervical lymph node micrometastasis in oral squamous cell carcinoma / 中华口腔医学杂志
Chinese Journal of Stomatology
;
(12): 221-223, 2004.
Article
in Chinese
| WPRIM
| ID: wpr-263411
ABSTRACT
<p><b>OBJECTIVE</b>To probe the relationship between lymphangiogenesis and cervical lymph node micrometastasis in oral squamous cell carcinoma.</p><p><b>METHODS</b>The microlymphatic vessel density was detected with enzyme histo-chemical method in 47 cases of oral squamous cell carcinoma and 10 cases of normal oral mucosa; 355 lymphnodes were detected with immunohistochemically using monoantibody AE3.</p><p><b>RESULTS</b>The mean MLVD was 14.04 +/- 6.92 in tumor group, or 5.48 +/- 2.62 in normal group. The difference was (P < 0.001). The percentage of tumor with expression CK was 48.9%. The mean MLVD was 16.94 +/- 5.43 in CK positive group, or 11.26 +/- 5.00 in CK negative group, There was difference significant (P < 0.001).</p><p><b>CONCLUSIONS</b>Lymphangiogenesis plays a key role in cervical lymph node micrometastasis of oral squamous cell carcinoma.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
General Surgery
/
Mouth Neoplasms
/
Carcinoma, Squamous Cell
/
Lymphangiogenesis
/
Lymph Node Excision
/
Lymph Nodes
/
Lymphatic Metastasis
/
Neck
Limits:
Humans
Language:
Chinese
Journal:
Chinese Journal of Stomatology
Year:
2004
Type:
Article
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