Polymorphism of CYP1A1 gene Msp I site in the Mongolian and Han nationality populations of Inner Mongolia of China / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
;
(6): 333-334, 2006.
Article
in Chinese
| WPRIM
| ID: wpr-263782
ABSTRACT
<p><b>OBJECTIVE</b>To study the polymorphism of CYP1A1 gene Msp I site in the Mongolian and Han nationality populations of Inner Mongolia.</p><p><b>METHODS</b>The PCR-restriction fragment length polymorphism(PCR-RFLP) technique was used to analyze the genotypes of CYP1A1 gene Msp I site in 80 subjects of Mongolian nationality and 120 subjects of Han nationality among whom there is no blood relationship each other.</p><p><b>RESULTS</b>The genotype frequency of CYP1A1 gene Msp I site showed that the wild-type, heterozygote, homozygous variants were 35.0%, 48.7%, 16.3% and 33.3%, 52.5%, 14.2% respectively distributions of Mongolian nationality and Han nationality population, and the Chi-square tests showed that there was no significant difference between the two groups.</p><p><b>CONCLUSION</b>The genotype frequency distributions of CYP1A1 gene Msp I site did not exhibit the obvious difference between Mongolian nationality and Han nationality population of Inner Mongolia.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Polymorphism, Genetic
/
Binding Sites
/
Polymorphism, Restriction Fragment Length
/
China
/
Polymerase Chain Reaction
/
Deoxyribonuclease HpaII
/
Cytochrome P-450 CYP1A1
/
Ethnology
/
Gene Frequency
/
Genetics
Limits:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Chinese Journal of Medical Genetics
Year:
2006
Type:
Article
Similar
MEDLINE
...
LILACS
LIS