Genetic polymorphisms of 10 X chromosome STR loci in a Chinese Tibetan population / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
;
(6): 97-99, 2006.
Article
in Chinese
| WPRIM
| ID: wpr-263840
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the alleles and genotypes frequency of 10 short tandem repeat (STR) loci on the X chromosome(DXS7423, DXS8378, DXS6799, DXS7424, DXS7130, DXS7132, DXS6789, DXS101, DXS6804, DXS7133) of Tibetan individuals living in Xizang Autonomous Region, Southwest China.</p><p><b>METHODS</b>The 10 X-chromosomal STR loci were analyzed with PCR, followed by polyacylamide gel electrophoresis and silver staining.</p><p><b>RESULTS</b>Among unrelated Tibetan individuals, the numbers of alleles in the 10 X-STR loci(DXS7423, DXS8378, DXS6799, DXS7424, DXS7130, DXS7132, DXS6789, DXS101, DXS6804, DXS7133) were 5, 5, 5, 9, 7, 7, 11, 9, 5 and 4, respectively. The genotype frequencies in females were in accordance with Hardy-Weinberg equilibrium.</p><p><b>CONCLUSION</b>The 10 X-chromosomal STRs loci are appropriate for individual identification, for paternity testing involving a female child, and for studies on related disease.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Polymorphism, Genetic
/
Ethnicity
/
China
/
Tibet
/
Tandem Repeat Sequences
/
Chromosomes, Human, X
/
Asian People
/
Ethnology
/
Genetics
/
Genetics, Population
Limits:
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Chinese Journal of Medical Genetics
Year:
2006
Type:
Article
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