Chemical constituents of n-BuOH extract of Comastoma pedunculatum / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 2360-2365, 2012.
Article
in Zh
| WPRIM
| ID: wpr-263926
Responsible library:
WPRO
ABSTRACT
Thirteen compoumds were isolated from the n-BuOH portion of the 70% ethanolic extract of Comastoma pedunculatum by a combination of various chromatographic techniques including silica gel, macroporous adsorbent resin, Sephadex LH-20, and preparative HPLC, of which nine were triterpenoid saponins and four were flavone C-glycosides. Their structures were elucidated by spectroscopic data as saikogenin F (1), 3-O-beta-D-fucopyranosylsaikogenin F (2), clinoposaponin XV (3), saikosaponin A (4), 6"-acetylsaikosaponin A (5), clinoposaponin I (6), bupleuroside I (7) , clinoposaponin XII (8) , saikoponin b3 (9), isovitexin (10) , swertisin (11) , isoorientin (12), 3',4',5-trihydroxy-7-methoxy-6-C-beta-D-glucopyranosyl-flavone (13). Compounds 1-10, 12-13 were all isolated from Comastoma genus for the first time.
Full text:
1
Index:
WPRIM
Main subject:
Saponins
/
Drugs, Chinese Herbal
/
Chemistry
/
Chromatography, High Pressure Liquid
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Spectrometry, Mass, Electrospray Ionization
/
Gentianaceae
/
Flavones
Language:
Zh
Journal:
China Journal of Chinese Materia Medica
Year:
2012
Type:
Article