Study on preventive effect of jiangu granule on osteoporosis in ovariectomized rats / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
;
(12): 369-371, 2002.
Article
in Chinese
| WPRIM
| ID: wpr-264137
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the preventive effect of Jiangu granule (JGG) on experimental primary osteoporosis type I.</p><p><b>METHODS</b>Osteoporosis model was established through ovary resection of female rats. Bone mineral density (BMD) was measured with double energy X-ray absorptiometry. Level of endocrine markers, including osteocalcin (BGP), estradiol (E2) and calcitonin (CT) in serum were examined by RIA. And uterus parameters was calculated also.</p><p><b>RESULTS</b>JGG could significantly increase BMD and uterus index, improve the levels of E2 and CT in serum, at the same time reduce the BGP level.</p><p><b>CONCLUSION</b>JGG can efficiently prevent type I primary osteoporosis or delay its occurrence by enhancing the function of endocrine system, coordinating the action of calcium related hormone, reducing bone turnover rate and increasing BMD.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Osteoporosis
/
Pharmacology
/
Blood
/
Calcitonin
/
Drugs, Chinese Herbal
/
Ovariectomy
/
Random Allocation
/
Bone Density
/
Osteocalcin
/
Rats, Sprague-Dawley
Limits:
Animals
Language:
Chinese
Journal:
Chinese Journal of Integrated Traditional and Western Medicine
Year:
2002
Type:
Article
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