Study on abnormality and regulation of T-lymphocyte subsets in peripheral blood of rheumatoid arthritis patients / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
;
(12): 359-361, 2002.
Article
in Chinese
| WPRIM
| ID: wpr-264140
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the change of T-lymphocyte subsets in peripheral blood of rheumatoid arthritis (RA) patients and analyze the effects of Fuzheng Qubi Decoction (FZQBD) on T-cell subsets.</p><p><b>METHODS</b>Thirty RA patients were randomly divided into two groups, and treated with FZQBD or western medicine combination therapy respectively for one month, the percentage of peripheral CD3+, CD4+, CD8+ as well as the serum IgG and IgA levels were determined.</p><p><b>RESULTS</b>The percentage of peripheral CD4+, CD4+/CD8+ ratio, IgG and IgA levels increased significantly (P < 0.001) in RA patients before treatment. After 1 month of FZQBD treatment, the CD4+/CD8+ ratio decreased obviously (P < 0.05).</p><p><b>CONCLUSION</b>Abnormal cellular immunity exists in RA patients, FZQBD could adjust the abnormal T-lymphocyte subsets to normalize it.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Arthritis, Rheumatoid
/
Drugs, Chinese Herbal
/
Anti-Inflammatory Agents, Non-Steroidal
/
Diclofenac
/
T-Lymphocyte Subsets
/
CD4-CD8 Ratio
/
Therapeutic Uses
/
Drug Therapy
/
Drug Therapy, Combination
/
Allergy and Immunology
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Integrated Traditional and Western Medicine
Year:
2002
Type:
Article
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