Effect of micronutrient supplementation on the growth of preschool children in China / 生物医学与环境科学(英文)
Biomedical and Environmental Sciences
;
(12): 196-202, 2002.
Article
in English
| WPRIM
| ID: wpr-264317
ABSTRACT
<p><b>OBJECTIVE</b>To study the relationship between micronutrient supplementation and children growth.</p><p><b>METHODS</b>A double-blind, placebo-controlled trial was conducted in 156 growth retarded preschool children. They were randomly assigned to five groups supplemental control (S-control, n = 28), zinc supplementation (+Zn, 3.5 mg Zn/day, n = 34), zinc and calcium supplementation (+ZnCa, 3.5 mg Zn + 250 mg Ca/day, n = 37), zinc and calcium and vitamin A supplementation (+ZnCaVA, 3.5 mg Zn + 250 mg Ca + 200 g VA/day, n = 28), Calcium, and vitamin A supplementation (+CaVA, 250 mg Ca + 200 g VA/day, n = 29). Another 34 children with normal height were selected as normal control (N-control). Supplementation continued for twelve months.</p><p><b>RESULTS</b>The height gain in +Zn group (7.84 cm per year) and +ZnCa group (7.70 cm per year) was significantly higher than that in S-control group (6.74 cm per year, P < 0.05); The weight gain in +ZnCaVA group (2.55 kg per year) and +CaVA group (2.57 kg per year) was also significantly higher than that in S-control group (2.19 kg per year, P < 0.05); The average days of illness in each supplementation group were lower than that in S-control (13 days per year compared with 23 days per year). No significant difference was observed on bone age.</p><p><b>CONCLUSION</b>Zinc and Zinc + Calcium supplementation can improve the height gain, and vitamin A can improve weight gain in growth retarded preschool children, but do not affect the maturity of bone. Micronutrient supplementation can lower the morbidity of these children.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Vitamin A
/
Zinc
/
Body Height
/
Weight Gain
/
Child Development
/
China
/
Calcium
/
Nutritional Status
/
Dietary Supplements
Type of study:
Controlled clinical trial
Limits:
Child, preschool
/
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
English
Journal:
Biomedical and Environmental Sciences
Year:
2002
Type:
Article
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