Tuberculosis control priorities defined by using cost-effectiveness and burden of disease / 生物医学与环境科学(英文)
Biomedical and Environmental Sciences
;
(12): 172-176, 2002.
Article
in English
| WPRIM
| ID: wpr-264320
ABSTRACT
<p><b>OBJECTIVE</b>To define TB control priorities using cost-effectiveness and burden of disease.</p><p><b>METHODS</b>An assumed cohort of 2,000 cases was set up based on age-specific incidence of 794 newly registered smear-positive cases in Beijing in 1994. Prognostic trees and model diagrams of infectivity with natural history and DOTS intervention were constructed based on the epidemiological parameters.</p><p><b>RESULTS</b>DOTS reduced 89.19% of YLL, 78.90% of YLD, and 99.98% of infectivity BOD. One DALY could be saved with 45.70 Yuan by DOTS with 3% discount. Sensitivity analysis showed that discount had effect on CER. Weight of age was insensitive to CER. The higher the DOTS cured rate, the more the cost-effectiveness.</p><p><b>CONCLUSIONS</b>DOTS is a good cost-effectiveness TB control strategy. Cost-effectiveness and burden of disease can be used to define TB control priorities.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Tuberculosis
/
China
/
Epidemiology
/
Cohort Studies
/
Cost-Benefit Analysis
/
Cost of Illness
/
Disabled Persons
/
Quality-Adjusted Life Years
/
Economics
/
Forecasting
Type of study:
Etiology study
/
Health economic evaluation
/
Incidence study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Biomedical and Environmental Sciences
Year:
2002
Type:
Article
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