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Effect of weight loss induced by laparoscopic adjustable gastric banding on immunity of morbid obesity / 中华外科杂志
Chinese Journal of Surgery ; (12): 309-312, 2005.
Article in Chinese | WPRIM | ID: wpr-264518
Responsible library: WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To compare the immunity of morbid obesity (MO) before and after laparoscopic adjustable gastric banding (LAGB).</p><p><b>METHODS</b>15 cases, with a mean body mass index (BMI) of 35.8 kg/m(2), were treated by LAGB from Jun. 2003 to Oct. 2003 in our department. Patients' immune parameters were determined preoperatively and 1, 3 and 6 months postoperatively. 15 cases with a normal BMI (23.6 kg/m(2)) were set as controls.</p><p><b>RESULTS</b>Before surgery, the MO had a significant lower level of CD(4)(+), CD(4)(+)/CD(8)(+) and a higher level of serum interleukin-2 (IL-2), Interleukin-6 (IL-6) than the controls (P < 0.01). There was a significant reduction of weight and BMI 6 months postoperatively (P < 0.01). At the same time, CD(4)(+) increased and serum IL-2 decreased significantly. But CD(4)(+)/CD(8)(+)and serum IL-2, IL-6 were still abnormal compare to the controls.</p><p><b>CONCLUSIONS</b>MO may combined with an abnormal immunity. But after enough weight loss induced by LAGB, it can be partly reversed.</p>
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Full text: Available Index: WPRIM (Western Pacific) Main subject: General Surgery / Obesity, Morbid / Female / Humans / Male / Gastroplasty / Weight Loss / Follow-Up Studies / Adolescent / Laparoscopy Language: Chinese Journal: Chinese Journal of Surgery Year: 2005 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: General Surgery / Obesity, Morbid / Female / Humans / Male / Gastroplasty / Weight Loss / Follow-Up Studies / Adolescent / Laparoscopy Language: Chinese Journal: Chinese Journal of Surgery Year: 2005 Type: Article