Isolation and identification of chemical constituents of fruits of Acanthopanax sessiliflorus / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To isolate and elucidate the chemical constituents of the fruits of Acanthopanax sessiliflorus.</p><p><b>METHOD</b>Isolation and purification were carried out on the column chromatography of silica gel and Sephadex LH-20. Their structures were elucidated on basis of physicochemical properties and spectral data.</p><p><b>RESULT</b>Nine compounds were isolated and identified as oleanolic acid-3-O-6'-O-methyl-beta-D-glucuronopyranoside (1), 22-alpha-hydroxychiisanogenin (2), oleanolic acid-3-O-beta-D-glucuronopyranoside (3), oleanolic acid-3-O-beta-D-glucopyranoside (4), oleanolic acid (5), chiisanogenin (6), (-)-sesamin (7), daucosterol (8), beta-sitosterol (9).</p><p><b>CONCLUSION</b>Compound 1 is obtained from the genus Acanthopanax genus for the first time. Compounds 2-5 are isolated from this plant for the first time.</p>