Studies on chemical constituents from roots of Angelica polymorpha / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the chemical constituents of the roots of Angelica polymorpha.</p><p><b>METHOD</b>Silica gel column chromatography was employed for the isolation and purification of chemical constituents. The structures were identified on the basis of spectral data and chemical evidence.</p><p><b>RESULT</b>Fourteen compounds were isolated and identified as follows, 5-hydroxy-2-[(angeloyloxy) methyl] furan [3', 2' 6, 7] chromone (1), octacosanoic acid (2), isoimperatorin (3), 3'S-(-)-O-acetylhamaudol (4), bergapten (5), iso-oxypeucedanin (6), beta-sitosterol (7), angeliticin A (8) , saxalin (9), pabulenol (10), noreugenin (11), oxypeucedanin hydrate (12), daucosterol (13), sucrose (14).</p><p><b>CONCLUSION</b>Compound 1 is a new chromone, named polymorchromone A. Compounds 2, 4, 11, 13, 14 were isolated from A. polymorpha for the first time.</p>