Association of the serum testosterone level with metabolic syndrome in men / 中华男科学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the association of the serum testosterone (T) level with metabolic syndrome (MS).</p><p><b>METHODS</b>We enrolled in this investigation 1,006 men aged 30-60 years in Beijing and obtained the data on their blood pressure (BP), waist circumference (WC), fasting blood glucose (FBG), serum triglycerides (TG), high density lipoprotein-cholesterol (HDL-C) and serum testosterone (T). The men were divided into an MS group and a non-MS (NMS) group based on The Chinese Adult Dyslipidemia Prevention Guide 2007. The results were compared and analyzed.</p><p><b>RESULTS</b>There was no statistically significant difference between the ages of the two groups (P >0.05). Systolic BP (SBP), diastolic BP (DBP), WC, FBG and TG were significantly higher, while serum T and HDL-C remarkably lower in the MS than in the NMS group (P <0.001). The serum T level was markedly decreased with the increase of MS components (P <0.01). Both Pearson's correlation coefficients and multiple linear regression analyses showed that the serum T level was negatively correlated with age, WC, SBP and TG (P < 0.05).</p><p><b>CONCLUSION</b>Low serum T level may predict the development of MS in men.</p>