Globozoospermia syndrome: an update / 中华男科学杂志
National Journal of Andrology
;
(12): 59-62, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-266210
ABSTRACT
Globozoospermia syndrome is a rare teratozoospermia, with an incidence of less than 0.1%. It is characterized by round sperm head, absence of acrosome, and messy sperm body and tail, but without other special clinical features. The absence of acrosome could reduce the activation ability of oocytes, and consequently decrease their fertilization ability. The assisted reproductive technique remains the only means for such patients to produce offspring. The pathogenesis of globozoospermia syndrome is not yet clear, though it is found to be related with 4 genes in the mouse and 1 on the human autosome. This article gives an overview on the clinical features, pathogenesis and genetics of globozoospermia syndrome, as well as the fertilizability and reproductivity of such patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Sperm Head
/
Spermatozoa
/
Genetics
/
Infertility, Male
Limits:
Animals
/
Humans
/
Male
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2011
Type:
Article
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