Recent development in ectopic reconstitution of seminiferous tubules / 中华男科学杂志
National Journal of Andrology
;
(12): 928-932, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-266241
ABSTRACT
The testicular development and spermatogenesis of mammalians involve complex processes of cell migration, proliferation and differentiation and cell-cell interaction. In spite of extensive researches, many relevant aspects remain unclear. One of the impediments in the studies of testicular development and spermatogenesis of mammalians is the lack of a suitable model. In the last few years, two valuable models were developed for the study of mammalian spermatogenesis testis tissue from immature animals transplanted ectopically into immunodeficient mice that could survive and produce functional spermatids, and isolated testis cells able to organize and rearrange into seminiferous cords that subsequently undergo complete spermatogenesis. This article presents an update and the applications and prospects of these two methods.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Seminiferous Tubules
/
Spermatogenesis
/
Transplantation
/
Cell Culture Techniques
Limits:
Animals
/
Humans
/
Male
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2010
Type:
Article
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