A meta-analysis of the safety of simultaneous versus staged resection for synchronous liver metastasis from colorectal cancer / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery
;
(12): 337-341, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-266347
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the safety of simultaneous and staged resection for synchronous liver metastasis from colorectal cancer.</p><p><b>METHODS</b>PubMed/Medline, ISI Web of Knowledge, Springer link, ebscohost, Elsevier Wiley Interscience, Google Scholar were searched for case-control studies concerning simultaneous versus staged resection of synchronous liver metastasis from colorectal cancer between January 1989 and March 2009. A meta-analysis was performed to analyze the morbidity and perioperative mortality.</p><p><b>RESULTS</b>Seven case-control studies, with a total of 1390 patients of liver metastasis from colorectal cancer undergone curative hepatic resection, were reviewed. There were 495 simultaneous and 895 staged resections. Perioperative mortality was 1.1% in the staged resection group and 2.4% in the the simultaneous group, the difference was statistically significant[Peto OR 3.39, 95% CI 1.29-8.93, P=0.01]. No significant difference was found in morbidity between two groups[OR(random)0.88, 95% CI 0.51-1.51, P=0.64].</p><p><b>CONCLUSION</b>Selective staged resection is safe for synchronous liver metastasis from colorectal cancer.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
General Surgery
/
Colorectal Neoplasms
/
Hepatectomy
/
Liver Neoplasms
/
Neoplasm Staging
Type of study:
Observational study
/
Systematic reviews
Limits:
Humans
Language:
Chinese
Journal:
Chinese Journal of Gastrointestinal Surgery
Year:
2010
Type:
Article
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