Impact of micronutrients on immunocyte and microelements status among people living with HIV / 中华流行病学杂志

ABSTRACT

Objective To explore the impact of micronutrients supplement on immunocyte and microelements status in HIV positive people. Methods Volunteers aged 25-49 years old were randomly selected and distributed into two groups. Supplement and placebo were given to the two groups. At the beginning of the trial, data on physical examination, immunocyte and microelements level in serum of the two groups were collected and showed no significant difference (P>0.05). Results After 6 months, the amount of immunocyte(CD4+, CD8+,CD3+) were (2078±108) mm3, (582±75) mm3, (1287±97) mm3 in the study group while they were (1436±105) mm3, (472±61)mm3, (998±84) mm3 in the control group, with statistically significant difference (P<0.05). Amounts of serum Zn, Ca, Mg, Fe showed (144.89±9.78) μmol/L, (1.89±0.19) μmol/L, (1.68±0.12) μmol/L, (152.61±8.94) μmol/L in the study group and they were (102.67±5.45) μmol/L, (1.13±0.07) μmol/L, (0.85±0.05) μmol/L, (89.24±3.91) μmol/L in the control group, with statistically significant difference(P<0.05). Conclusion Supplementation of micronutrients could increase the levels of Zn, Ca, Mg, Fe so as to increase the immune function in people living with HIV.