IC-kmedoids: a clustering algorithm for RNA secondary structure prediction / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 99-103, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-266719
ABSTRACT
Due to the minimum free energy model, it is very important to predict the RNA secondary structure accurately and efficiently from the suboptimal foldings. Using clustering techniques in analyzing the suboptimal structures could effectively improve the prediction accuracy. An improved k-medoids cluster method is proposed to make this a better accuracy with the RBP score and the incremental candidate set of medoids matrix in this paper. The algorithm optimizes initial medoids through an expanding medoids candidate sets gradually. The predicted results indicated this algorithm could get a higher value of CH and significantly shorten the time for calculating clustering RNA folding structures.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Algorithms
/
RNA
/
Cluster Analysis
/
Chemistry
/
Nucleic Acid Conformation
Type of study:
Prognostic study
Language:
Chinese
Journal:
Journal of Biomedical Engineering
Year:
2015
Type:
Article
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