Regulatory T Cells in Hepatitis B and C Virus Infections
Immune Network
;
: 330-336, 2016.
Article
in English
| WPRIM
| ID: wpr-26675
ABSTRACT
Hepatitis B virus (HBV) and hepatitis C virus (HCV) are hepatotropic viruses that establish chronic persistent infection by effectively escaping the host immune response and can cause immune-mediated liver injury. It has recently become apparent that regulatory T (Treg) cells, specifically CD4⁺CD25⁺Foxp3⁺ Treg cells, modulate viral diseases by suppressing antiviral immune responses and regulating inflammatory host injury. The roles of Treg cells in HBV and HCV infections range from suppressing antiviral T cell responses to protecting the liver from immune-mediated damage. This review describes Treg cells and subpopulations and focuses on the roles of these cells in HBV and HCV infections.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
United Nations
/
Virus Diseases
/
Hepatitis B virus
/
T-Lymphocytes, Regulatory
/
Hepacivirus
/
Hepatitis
/
Hepatitis B
/
Liver
Language:
English
Journal:
Immune Network
Year:
2016
Type:
Article
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