Measurement method of arterial shear stress of rats model based on ultrasonic particle imaging velocimetry / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 1355-1360, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-266750
ABSTRACT
The development and progression of atherosclerosis and thrombosis are closely related to changes of hemodynamics parameters. Ultrasonic pulse wave Doppler technique is normally used for noninvasively blood flow imaging. However, this technique only provides one-dimensional velocity and depends on the angle between the ultrasound beam and the local velocity vector. In this study, ultrasonic particle image velocimetry method was used to assess whole field hemodynamic changes in normal blood vessels. By using the polynomial fitting method, we investigated the velocity gradient and assessed the shear in different blood flow velocity of 10 healthy rats. It was found that using four polynomial fitting could result in optimal measurement results. The results obtained by ultrasonic particle image velocimetry accorded with the results obtained using Doppler technique. The statistical average of cyclical vessel wall shear stress was positively related to the locational mean velocity. It is proven that ultrasonic particle image velocimetry method could be used to assess directly the real-time whole field hemodynamic changes in blood vessels and was non-invasively, and should be a good prosperous technique for monitoring complex blood flow in stenotic ar- teries.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Arteries
/
Rheology
/
Stress, Mechanical
/
Ultrasonics
/
Blood Flow Velocity
/
Algorithms
/
Diagnostic Imaging
/
Echocardiography, Doppler
/
Hemodynamics
Type of study:
Diagnostic study
Limits:
Animals
Language:
Chinese
Journal:
Journal of Biomedical Engineering
Year:
2014
Type:
Article
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