Effects of electroacupuncture on neurological deficit and pathomorphologic lesion in the rat of focal cerebral ischemia / 中国针灸

ABSTRACT

<p><b>OBJECTIVE</b>To probe into regularity of effects of electroacupuncture on focal cerebral infarction.</p><p><b>METHODS</b>Focal cerebral ischemia model was established by middle cerebral artery heat-occlusion (MACO) method. Electroacupuncture was given at Dazhui (GV 14) and Baihui (GV 20). NSS was used for evaluation of neurological impairment, TTC staining method for detection of the infarct volume, and HE staining method for investigation of the pathomorphologic lesion of the brain.</p><p><b>RESULTS</b>MCAO could induce neurologic impairment, cerebral infarction and cerebral pathological lesion in the rat, all of these changes could be cured spontaneously in varying degrees with prolongation of ischemic time, but electroacupuncture could relieve the lesions to a certain extents.</p><p><b>CONCLUSION</b>Electroacupuncture can improve neurologic deficit impairment, reduce the volume of cerebral infarction and ischemic pathological lesion, early interfere of acupuncture and moxibustion is of very important clinical significance for treatment of ischemic apoplexy.</p>