A comparative study on the risks of esophagus-cancer patients among factors as blood relatives,paternal line,matriarchal and different sex / 中华流行病学杂志
Chinese Journal of Epidemiology
;
(12): 409-412, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-267360
ABSTRACT
Objective In order to provide new clues on the cause of esophagus-cancer through seeking for information among the relatives of esophagus-cancer-patients at high-risk,contrast analysis was carried out to compare the ORs between esophagus-cancer cases and the relatives of the patients.Methods Case-control study was adopted on 720 cases and 720 controls who were kin relatives of the patients.Results (1) Risk of the relatives to the esophagus-cancer-patient group ( 1.34%-2.24% ) was obviously higher than the control group (0.78%-1.21%) (P<0.01).In 1st grade relatives,the risk of parent' s to the esophagus-cancer patients (6.11% ) was obviously higher than the control group (2.97%) (P<0.01 ).(2) According to the cascade analysis to the cases of both paternal and matriarchal,lines,results showed that the risks of both the paternal line (0.87%-1.01%) and the matriarchal line (0.50%-0.79%) in the group of esophagus-cancer cases were all obviously higher than the lines in the control groups (0.53%-0.65%) and (0.38%-0.47%).Data also showed that the risk among the male relatives of paternal line (eggrandfathers',father' s,uncles' etc.) in the group of cases was 2.68% while the matriarchal (eggrandmother's,mother' s,aunts' etc.) was 1.91%.Both figures were obviously higher than that in the control group (1.50% and 0.92%,P<0.01 ).Conclusion The risk factor of esophagus cancer of the next generation seemed higher if the father and his brothers or mother and her sisters having had esophagus-cancers.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Etiology study
/
Observational study
/
Risk factors
Language:
Chinese
Journal:
Chinese Journal of Epidemiology
Year:
2010
Type:
Article
Similar
MEDLINE
...
LILACS
LIS