A community-based study on relations between metabolic syndrome and carotid atherosclerosis in a middle-aged population / 中华流行病学杂志
Chinese Journal of Epidemiology
;
(12): 361-365, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-267370
ABSTRACT
Objective To explore the association between metabolic syndromes (MS) and carotid atherosclerosis and to estimate the predictive effects of MS under 3 different definitions.Methods A cross-sectional study was conducted in 2 community-based populations in Beijing,in 2008.1266 subjects (598 men,668 women),aged 45-69,were included in the analyses.MS was defined by the criteria of International Diabetes Federation (IDF),the revised NCEPATPm (ATP Ⅲ-R) and "The Guidelines of Dyslipidemia Control for Chinese Adult" ( "Guidelines" ) in 2007.Results The prevalence rates of MS by the 3 criteria were 39.0%,43.3% and 30.9% respectively.The Kappa value for the measure of the agreement between each pair of the 3 definitions were 0.911,0.719 and 0.730 respectively.The intima-media thickness in common carotid artery (CCA-IMT) was significantly higher (P<0.001) in all MS groups than in non-MS groups,diagnosed with the 3 criteria independent of age,gender,LDL-C,and current smoking status.After adjustment of age,gender,LDL-C,and current smoking status,the classification of MS significantly increased the risk of prevalence of carotid atberosclerotic plaques,compared to the non-MS group.OR value were 1.499 (95% CI1.157-1.942) for IDF,1.696 (95% CI1.314-2.189) for NCEP-R,1.763 (95% CI1.344-2.312) for "Guideline" respectively.Conclusion Our research findings indicated that,when MS were defined with the 3 definitions,prediction on the risk of sub-clinical atberosclerosis would work beyond some of the conventional cardiovascular risk factors such as smoking,LDL-C.There might exist some differences in gender issue on the strength of association between MS when diagnosed by different criteria and carotid plaque.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Practice guideline
/
Observational study
/
Prognostic study
/
Risk factors
Language:
Chinese
Journal:
Chinese Journal of Epidemiology
Year:
2010
Type:
Article
Similar
MEDLINE
...
LILACS
LIS