Distribution of HCV genotypes in volunteer blood donors in Guangzhou / 南方医科大学学报
Journal of Southern Medical University
;
(12): 2655-2657, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-267715
ABSTRACT
<p><b>OBJECTIVE</b>To determine the distribution of HCV genotypes among volunteer blood donors in Guangzhou.</p><p><b>METHODS</b>Six-nine HCV RNA-positive samples were collected from volunteer blood donors in Guangzhou. NS5B fragments of HCV were amplified followed by DNA sequencing and phylogenetic analysis.</p><p><b>RESULTS</b>HCV genotypes were determined for 67 samples. Among them, the subtypes 1b, 2a, 3a, 3b, 6a and 6n were detected at the frequencies of 37.31%, 4.48%, 7.46%, 4.48%, 44.78% and 1.49%, respectively.</p><p><b>CONCLUSION</b>HCV 1b and 6a are the most predominant two subtypes among volunteer blood donors in Guangzhou.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Phylogeny
/
Blood Donors
/
RNA, Viral
/
China
/
Classification
/
Sequence Analysis, DNA
/
Hepacivirus
/
Genetics
/
Genotype
Limits:
Humans
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Journal of Southern Medical University
Year:
2010
Type:
Article
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