Effect of obstructive sleep apnea hypopnea syndrome on arterial stiffness / 南方医科大学学报
Journal of Southern Medical University
;
(12): 2652-2654, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-267716
ABSTRACT
<p><b>OBJECTIVE</b>To assess the effect of obstructive sleep apnea hypopnea syndrome (OSAHS) on brachial-ankle pulse wave velocity (b-aPWV) in untreated diagnosed patients.</p><p><b>METHODS</b>This study involved 24 consecutive male patients with newly diagnosed untreated OSAHS (aged 39.13±8.31 years) and 22 normal male individuals (aged 39.59±10.86 years) matched for age and body mass index. Carotid and extremities ultrasound were performed in all the subjects, and none of them had atherosclerosis, arterial calcification, or aneurysm. No subject had a history of hypertension, coronary heart disease or stroke. All the subjects underwent arterial stiffness evaluation by means of b-aPWV measurements.</p><p><b>RESULTS</b>The b-aPWV in OSAHS patients was significantly higher than that in normal subjects (1346.86±123.48 vs 1237.91±84.46, P<0.01), and the rate of positive b-aPWV in OSAHS patients was significantly higher (13/24 vs 1/22, P<0.01).</p><p><b>CONCLUSION</b>The value and positive rate of b-aPWV in OSAHS patients are higher than those in normal people, suggesting increased arterial stiffness in OSAHS patients.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Arteries
/
Case-Control Studies
/
Sleep Apnea, Obstructive
/
Ankle Brachial Index
/
Vascular Stiffness
Type of study:
Observational study
Limits:
Adult
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Southern Medical University
Year:
2010
Type:
Article
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