Pre- and post-prostatectomy variation and supplement of sexual hormones in patients with benign prostatic hyperplasia / 中华男科学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To explore the variation of sexual hormones (T and fT) before and after prostatectomy and their post-operative supplement in patients with benign prostatic hyperplasia (BPH).</p><p><b>METHODS</b>Sixty-four cases of BPH were randomly divided into a treatment group (Group I, n = 25) and a control group (Group II, n = 39). Plasma LH, FSH, T and fT were measured by radioimmunoassay a week before and two weeks after prostatectomy. After operation, Group I received supplement of testosterone undecanoate, while Group II received none.</p><p><b>RESULTS</b>The variations of plasma LH, FSH, T and fT were not statistically significant in the two groups before prostatectomy (P > 0.05), but obviously less in Group I than in Group II after operation (P < 0.01).</p><p><b>CONCLUSION</b>Testosterone supplement is a useful therapy for post-prostatectomy patients with androgen deficiency.</p>