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Differentially expressed genes in prostate cancer and benign prostatic hyperplasia / 中华男科学杂志
National Journal of Andrology ; (12): 897-899, 2004.
Article in Chinese | WPRIM | ID: wpr-267787
ABSTRACT
<p><b>OBJECTIVE</b>To detect and analyze the differentially expressed genes in prostate cancer (PCa) and benign prostatic hyperplasia (BPH).</p><p><b>METHODS</b>Oligonucleotide microarray containing 465 genes was used to investigate the differentially expressed genes in PCa and BPH.</p><p><b>RESULTS</b>There were 35 differentially expressed genes between PCa and BPH, of which 17 were up-regulated and 18 down-regulated in PCa.</p><p><b>CONCLUSION</b>The study of the differentially expressed genes in PCa and BPH should help to understand the molecular mechanism of PCa and identify the markers for diagnostic and therapeutic use.</p>
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Prostatic Hyperplasia / Prostatic Neoplasms / Down-Regulation / Up-Regulation / Oligonucleotide Array Sequence Analysis / Gene Expression Profiling / Genetics / Metabolism Limits: Humans / Male Language: Chinese Journal: National Journal of Andrology Year: 2004 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Prostatic Hyperplasia / Prostatic Neoplasms / Down-Regulation / Up-Regulation / Oligonucleotide Array Sequence Analysis / Gene Expression Profiling / Genetics / Metabolism Limits: Humans / Male Language: Chinese Journal: National Journal of Andrology Year: 2004 Type: Article