Detection of free testosterone in the serum and semen of idiopathic oligospermia patients and its significance / 中华男科学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To detect free testosterone (FT) in the serum and semen of patients with idiopathic oligospermia, and further analyze the relationship between FT and idiopathic oligospermia.</p><p><b>METHODS</b>Blood samples were collected from the males of a normal control group (n = 44) and an idiopathic oligospermia group (n = 44) at 800-1000 a.m.. Semen samples were collected from the males of a normal control group (n = 30) and an idiopathic oligospermia group (n = 37) at the same time. Sperm density was detected by routine semen analysis, and FT in the serum and semen was detected by RIA.</p><p><b>RESULTS</b>There was no significant difference in the serum concentrations of FT between the groups of normal control [(97.50 +/- 46.96) pmol/L] and idiopathic oligospermia [(94.88 +/- 42.04) pmol/L], P > 0.5. But the difference was significant in the semen concentrations of FT between the groups of normal control [(2.01 +/- 0.32) pmol/L] and idiopathic oligospermia [(0.52 +/- 0.44) pmol/L], P < 0.01.</p><p><b>CONCLUSION</b>Measurement of semen FT concentration could early reflect the function of the testis, which contributes to the early diagnosis and treatment of idiopathic oligospermia.</p>