Research Progress of microRNAs and human hematological diseases - review / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 979-983, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-267845
ABSTRACT
The microRNAs (miRNAs) are an evolutionarily conserved class of 22 nucleotide (19 - 25 nt) non-coding RNAs. The miRNAs are partially complementary to 3' untranslated region of target mRNA, resulting in the repression of gene expression at post-transcriptional level. The miRNAs have been associated with diverse biological processes. This review summarizes recent progress of research on the characteristics and function of miRNAs, and the role of miRNAs in hematological malignancy development.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Physiology
/
Gene Expression Regulation, Neoplastic
/
Hematologic Neoplasms
/
MicroRNAs
/
Genetics
/
Metabolism
Limits:
Humans
Language:
Chinese
Journal:
Journal of Experimental Hematology
Year:
2008
Type:
Article
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