Impact of chronic prostatitis/chronic pelvic pain syndrome on sperm DNA fragmentation and nucleoprotein transition / 中华男科学杂志
National Journal of Andrology
;
(12): 907-911, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-268033
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the impact of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) on sperm DNA fragmentation and nucleoprotein transition.</p><p><b>METHODS</b>Based on the recommended methods in the WHO Laboratory Manual for the Examination and Processing of Human Semen (5th ed), we conducted routine semen analysis for 65 CP/CPPS patients and 30 healthy men. We also analyzed the results of papanicolaou staining, sperm DNA fragmentation and sperm nucleoprotein transition.</p><p><b>RESULTS</b>Compared with the healthy control males, the CP/CPPS patients showed significant decreases in sperm concentration ([134.05 +/- 99.80] vs [94.75 +/- 92.07]) x 10(6)/ml, P <0.05), the percentage of morphologically normal sperm ([7.26 +/- 2.28] vs [5.61 +/- 3.40]%, P <0.05) and sperm progressive motility ([59.18 +/- 16.06] vs [47.68 +/- 17.62]%, P<0.05), but dramatic increases in sperm DNA fragmentation ([22.92 +/- 11.51] vs [43.58 +/- 17.07%, P<0.01) and sperm nucleoprotein transition ([23.26 +/- 5.97] vs [32.14 +/- 8.79]%, P<0.01).</p><p><b>CONCLUSION</b>CP/CPPS significantly reduces sperm quality and male fertility.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prostatitis
/
Sperm Count
/
Sperm Motility
/
Case-Control Studies
/
DNA Fragmentation
/
Semen Analysis
/
Genetics
/
Nucleoproteins
Type of study:
Observational study
Limits:
Adult
/
Humans
/
Male
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2013
Type:
Article
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