Advances in the study of A2B adenosine receptor antagonists / 药学学报
Acta Pharmaceutica Sinica
;
(12): 241-246, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-268138
ABSTRACT
A2B adenosine receptor is involved in the control of mast cell degranulation, interleukin-8 synthesis and cell growth. A2B adenosine receptor antagonists may serve as novel drugs for asthma, Alzheimer' s disease, cystic fibrosis and type-II diabetes. Therefore, seeking for the highly selective A2B adenosine receptor antagonists has been one of great interest. The molecular basis, structure-activity relationship of selective A2B adenosine receptor antagonists and their interactions with A2B adenosine receptor were reviewed.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Pulmonary Artery
/
Asthma
/
Structure-Activity Relationship
/
Xanthines
/
Adenosine
/
Anti-Asthmatic Agents
/
Adenosine-5'-(N-ethylcarboxamide)
/
Therapeutic Uses
/
Drug Therapy
Limits:
Animals
/
Humans
Language:
Chinese
Journal:
Acta Pharmaceutica Sinica
Year:
2008
Type:
Article
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