Synthesis and molecule recognition capability of corilagin-molecularly imprinted polymer / 药学学报
Acta Pharmaceutica Sinica
;
(12): 1218-1221, 2007.
Article
in Chinese
| WPRIM
| ID: wpr-268202
ABSTRACT
To study the molecule recognition capability of corilagin-molecularly imprinted polymer (MIP) by the high performance liquid chromatography (HPLC), the molecularly imprinted polymer was synthesized by using corilagin as the template. Chromatographic performance of corilagin was investigated in different mobile phases. The MIP was investigated for the recognition of corilagin and its derivatives and other compounds in the same mobile phase. The MIP exhibited very high affinity for corilagin in the mobile phase of acetonitrile. The K' value will be reduced when the content of polar solvent increased in the mobile phase. The MIP has good selectivity in the mobile phase of acetonitrile-methanol (955), but it has no affinity for corilagin's derivatives. The corilagin-MIP has good selectivity for corilagin and it can be used in extracting corilagin and its analogs from herbs.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Acetonitriles
/
Polymers
/
Chemistry
/
Chromatography, High Pressure Liquid
/
Hydrolyzable Tannins
/
Glucosides
/
Methods
Language:
Chinese
Journal:
Acta Pharmaceutica Sinica
Year:
2007
Type:
Article
Similar
MEDLINE
...
LILACS
LIS