A Case of IgA Nephropathy Associated with Systemic Lupus Erythematosus / 대한류마티스학회지
The Journal of the Korean Rheumatism Association
;
: 54-58, 2009.
Article
in Korean
| WPRIM
| ID: wpr-26851
ABSTRACT
Renal involvement is frequently seen in patients with systemic lupus erythematosus (SLE). The occurrence of non-lupus nephritis, and especially IgA nephropathy, in SLE patients has rarely been reported. We describe here the case of a 30-year-old woman who had systemic lupus erythematosus and nontuberculous mycobacterial lung disease, and her biopsy of a renal lesion was unexpectedly diagnostic of IgA nephropathy. Although both IgA nephropathy and lupus nephritis are immune complex mediated diseases, their laboratory and histopathologic findings and the extra-renal clinical manifestations are different and these all support a different pathogenesis for the 2 diseases. Renal biopsy plays a crucial role in identifying and diagnosing renal lesions, which may have prognostic and therapeutic implications that are distinct from those of lupus nephritis. In conclusion, performing a renal biopsy in SLE patients who have urinary abnormalities is important since a correct diagnosis would permit the most appropriate treatment to be started and so avoid unnecessary immunosuppressive treatments.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Biopsy
/
Lupus Nephritis
/
Immunoglobulin A
/
Glomerulonephritis, IGA
/
Lung Diseases
/
Lupus Erythematosus, Systemic
/
Antigen-Antibody Complex
/
Nephritis
Type of study:
Prognostic study
Limits:
Adult
/
Female
/
Humans
Language:
Korean
Journal:
The Journal of the Korean Rheumatism Association
Year:
2009
Type:
Article
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