Histologic analysis and long-term effect of acellular dermal matrix combined with autologous thin split-thickness skin graft / 中华整形外科杂志

ABSTRACT

<p><b>OBJECTIVE</b>To evaluate the long-term therapeutic effect and histologic result of ADM combined with autologous thin split-thickness skin graft.</p><p><b>METHODS</b>23 patients were treated with acellular dermal matrix (ADM) combined with autologous thin split-thickness skin graft. The patients were followed up at 3, 6, 12, and 18 months after operation. The histological analysis was also performed.</p><p><b>RESULTS</b>3, 6, 12, 18 months after operation, the composite skin grafts became smooth with no hypertrophic scar and hyperpigmentation. It was soft and elastic. The joints could move randomly. The histologic study showed the composite skin graft had a similar appearance as the normal skin.</p><p><b>CONCLUSION</b>As for the treatment of wound, the composite skin graft with ADM is smooth and soft with good elasticity after transplantation, but it has no perspiration.</p>