The expression of CEACAM-1 and CXCL-14 in infantile hemangioma / 中华整形外科杂志
Chinese Journal of Plastic Surgery
;
(6): 195-198, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-268707
ABSTRACT
<p><b>OBJECTIVE</b>To examine the expression of CEACAM-land CXCL-14 in the different stages of infantile hemangioma and to explore the role of CEACAM-1 and CXCL-14 in the occurrence and development of infantile hemangioma.</p><p><b>METHODS</b>The expression of CEACAM-1 and CXCL-14 was detected by immunohistochemical technique and Western Blot in cases of proliferating hemangiomas, involuting hemangiomas, involuted hemangiomas. The mean optical density was measured by image analysis system.</p><p><b>RESULTS</b>The expression of CEACAM-1 in early stage of proliferating hemangiomas was weak or negative, while it was strong in involuting hemangiomas and positive in the involuted stage. The differences between different stages had a statistically significance (P < 0.05). The expression of CXCL-14 was weak or negative in stage of proliferating hemangiomas, positive in involuting hemangiomas and strong in the involuted stage. The differences between different stages had a statistically significance (P < 0.05).</p><p><b>CONCLUSIONS</b>CEACAM-1 and CXCL-14 are involved in the occurrence and development of infantile hemangioma.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Antigens, CD
/
Cell Adhesion Molecules
/
Chemokines, CXC
/
Hemangioma
/
Metabolism
Limits:
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Language:
Chinese
Journal:
Chinese Journal of Plastic Surgery
Year:
2010
Type:
Article
Similar
MEDLINE
...
LILACS
LIS