Serological observation of Toxoplasma gondii prevalence in Apodemus agrarius, a dominant species of field rodents in Korea
Yonsei Medical Journal
;
: 491-496, 2000.
Article
in English
| WPRIM
| ID: wpr-26879
ABSTRACT
Field rodents involved in ecological food chains and which are the prey of carnivores in the natural environment may serve as reservoir hosts for Toxoplasma gondii infection in humans, however, no data has been published to date in Korea. A total of 1,008 Apodemus agrarius, a dominant species of field rodents in Korea, were trapped at various locations around the country, and their serum antibody (IgG) levels to T. gondii were examined by ELISA. The mean absorbance was 0.11, and fifteen samples (1.49%) showed positive titers from 0.18 to 0.59. The seropositive samples were analyzed by immunoblot. Five of them showed reactive bands to T. gondii water soluble antigens of 30, 35, and 43 kDa. This immunoblot analysis showed very similar patterns to that obtained using sera of experimentally infected mice with T. gondii. The present study presents indirect evidence of the existence of T. gondii in field rodents in Korea.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Toxoplasma
/
Enzyme-Linked Immunosorbent Assay
/
Antibodies, Protozoan
/
Immunoblotting
/
Seroepidemiologic Studies
/
Animals
/
Molecular Weight
/
Muridae
/
Antigens, Protozoan
Type of study:
Prevalence study
Language:
English
Journal:
Yonsei Medical Journal
Year:
2000
Type:
Article
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