Holmium laser enucleation versus open prostatectomy for large volume benign prostatic hyperplasia: a meta-analysis of the therapeutic effect and safety / 南方医科大学学报
Journal of Southern Medical University
;
(12): 882-885, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-268976
ABSTRACT
<p><b>OBJECTIVE</b>To compare holmium laser enucleation (HoLEP) versus open prostatectomy (OP) for large volume benign prostatic hyperplasia.</p><p><b>METHODS</b>The randomized controlled trials (RCTs) pertaining to HoLEP and OP for management of large volume benign prostatic hyperplasia were retrieved from Medline and Embase. Meta-analysis was performed using Review Manager 5.0 software.</p><p><b>RESULTS</b>Three RCTs were included in the analysis. No significant differences were found in IPSS or Qmax between HoLEP and OP (P>0.05). Compared with OP, HoLEP was associated with significantly less blood loss, a shorter catheterization time and a shorter hospital stay, but a longer operating time. HoLEP and OP were similar in terms of urethral stricture, stress incontinence, transfusion requirement and the rate of reintervention.</p><p><b>CONCLUSION</b>HoLEP and OP have similar therapeutic effects in the management of large volume benign prostatic hyperplasia. Although with a longer operating time and less resected tissue, HoLEP causes less blood loss and requires a shorter catheterization time and a shorter hospital stay. HoLEP has a comparable safety to OP in terms of the adverse events.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prostatectomy
/
Prostatic Hyperplasia
/
General Surgery
/
Randomized Controlled Trials as Topic
/
Lasers, Solid-State
/
Methods
Type of study:
Controlled clinical trial
/
Systematic reviews
Limits:
Humans
/
Male
Language:
Chinese
Journal:
Journal of Southern Medical University
Year:
2012
Type:
Article
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