Effect of clearing heat and removing dampness method on formation of pigment gallstones in rabbits / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
;
(12): 241-243, 2007.
Article
in Chinese
| WPRIM
| ID: wpr-269091
ABSTRACT
<p><b>OBJECTIVE</b>To observe dynamically the effect of drugs for clearing heat and removing dampness (CHRD) on biliary components in rabbits with pigment gallstones (PGS).</p><p><b>METHODS</b>Forty rabbits were established into PGS model and randomly divided into 3 groups, the bacterial infection group, the CHRD low-dose group and the CHRD high-dose group. Besides, a normal group was set up with healthy rabbits for control. Changes of total bilirubin (TB), unconjugated bilirubin (UCB), total bile acid (TBA), Ca2+, bacterial and endogenous beta-glucuronidase (beta-Gase) in bile were observed.</p><p><b>RESULTS</b>CHRD drugs significantly decreased the contents of UCB, Ca2+, bacterial and endogenous beta-Gase (P < 0.05), and increased TBA in bile (P < 0.05).</p><p><b>CONCLUSION</b>CHRD drugs have good effect in reducing the lithogenesis of the pigment gallstones.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Bile
/
Bile Pigments
/
Drugs, Chinese Herbal
/
Gallstones
/
Random Allocation
/
Calcium
/
Treatment Outcome
/
Therapeutic Uses
/
Drug Therapy
Type of study:
Prognostic study
Limits:
Animals
Language:
Chinese
Journal:
Chinese Journal of Integrated Traditional and Western Medicine
Year:
2007
Type:
Article
Similar
MEDLINE
...
LILACS
LIS