Study of intra-operative radiotherapy in primary liver cancer / 南方医科大学学报

ABSTRACT

<p><b>OBJECTIVE</b>To study the feasibility of intraoperative radiotherapy (IORT) in primary liver cancer.</p><p><b>METHODS</b>Based on the target of dose curves, the dose-volume histogram (DVH) and cost of radiation equipment and radiation therapy, IORT was compared with protonbeam therapy (PBT) and 3DCRT in 16 patients with primary liver cancer using the therapy plan system (TPS).</p><p><b>RESULTS</b>IORT had significantly better performance than 3DCRT to allow a target region surrounded by 90% of the dose lines. IORT was similar to protonbeam therapy in terms of target region surroundings and absorbed dose in the normal organs, but the cost of IORT was significantly lower.</p><p><b>CONCLUSION</b>The TPS of IORT is better than 3DCRT and similar to protonbeam therapy in the treatment of primary liver cancer with similar cost to 3DCRT. IORT can effectively protect the neighboring sensitive organs and improve the absorbed dose in the tumors and the local control rate.</p>