The advance of model of action in low-dose chronic benzene exposure induced hematotoxicity / 中华预防医学杂志
Chinese Journal of Preventive Medicine
;
(12): 840-843, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-269982
ABSTRACT
Benzene is classified as Group 1 carcinogen by IARC. It has been found that benzene induces hematotoxicity even in low dose exposure. The identification of key events during benzene induced hematotoxicty leads to adjustment of occupational exposure limits of benzene. In this review, we focus on the exposure, metabolism, target organs, key epigenetic changes, toxicty effects and end points of low-dose chronic benzene exposure induced hematotoxicity and finally discuss the perspectives on the future study of this area.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Benzene
/
Carcinogens
/
Occupational Exposure
/
Epigenesis, Genetic
/
Toxicity
Limits:
Humans
Language:
Chinese
Journal:
Chinese Journal of Preventive Medicine
Year:
2015
Type:
Article
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