Early diagnosis of female genital tuberculosis by phage amplified biological assay / 南方医科大学学报

ABSTRACT

<p><b>OBJECTIVE</b>To establish an early diagnostic method for detecting female genital tuberculosis.</p><p><b>METHODS</b>Eighty-six women with genital tuberculosis during January 2005-September 2007 were examined by phage amplified biological assay, and the results were compared with those from leucorrhea culture, smear and PCR.</p><p><b>RESULTS</b>Forty-five patients were tuberculosis positive with 100% of specificity identified by phage amplified biological assay. Twenty patients were tuberculosis positive by PCR. Five patients were culture-positive tuberculosis and no case had smear-positive tuberculosis.</p><p><b>CONCLUSION</b>Phage amplified biologically assay is sensitive and specific, which could be used for the early diagnosis of female genital tuberculosis.</p>