X-ray-induced expression changes of TNFSF4 gene in human peripheral blood / 生物医学与环境科学(英文)
Biomedical and Environmental Sciences
;
(12): 729-732, 2014.
Article
in English
| WPRIM
| ID: wpr-270546
ABSTRACT
This study examined ionizing radiation-induced tumor necrosis factor (ligand) superfamily, member 4 (TNFSF4) mRNA expression changes in human peripheral blood cells and their distribution in a normal population. The results showed that expression level of TNFSF4 mRNA exhibited a dose-dependent response after different irradiation doses, but that was independent of incubation time post-irradiation. Moreover, it was not affected by age and gender in 51 healthy donors. Our studies indicate that TNFSF4 can be considered as a candidate gene to develop a new biodosimeter.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Radiation Effects
/
X-Rays
/
Blood
/
Blood Cells
/
Biomarkers
/
Dose-Response Relationship, Radiation
/
OX40 Ligand
/
Healthy Volunteers
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
English
Journal:
Biomedical and Environmental Sciences
Year:
2014
Type:
Article
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