AduoLa Fuzhenglin down-regulates microwave-induced expression of β1-adrenergic receptor and muscarinic type 2 acetylcholine receptor in myocardial cells of rats / 生物医学与环境科学(英文)
Biomedical and Environmental Sciences
;
(12): 204-207, 2014.
Article
in English
| WPRIM
| ID: wpr-270614
ABSTRACT
This paper is aimed to study the effect of ADL on expression of β1-AR and M2-AchR in myocardial cells of rats exposed to microwave radiation. Immunohistochemistry, Western blot and image analysis were used to detect the expression of β1-AR and M2-AchR in myocardial cells at 7 and 14 d after microwave exposure. The results show that the expression level was higher in microwave exposure group and 0.75 g/(kg•d) ADL group than in sham operation group and significantly lower in 1.5 and 3.0 g/(kg•d) ADL groups than in microwave group. So we have a conclusion that the expression of β1-AR and M2-AchR is down-regulated in myocardial cells of rats exposed to microwave radiation. ADL can protect rats against microwave-induced heart tissue injury.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Drugs, Chinese Herbal
/
Down-Regulation
/
Rats, Wistar
/
Receptors, Adrenergic, beta-1
/
Protective Agents
/
Cell Biology
/
Receptor, Muscarinic M2
/
Heart
/
Metabolism
Limits:
Animals
Language:
English
Journal:
Biomedical and Environmental Sciences
Year:
2014
Type:
Article
Similar
MEDLINE
...
LILACS
LIS