Incidence of seroresistance of syphilis and its relevant factors / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 338-341, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-270693
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the incidence of seroresistance of syphilis and analyze its relevant factors.</p><p><b>METHODS</b>The clinical data of 131 patients with syphilis were retrospectively analyzed. The incidence of seroresistance was investigated and the correlation between seroresistance and factors including age, gender, original titer, disease course, and medications were analyzed.</p><p><b>RESULTS</b>The incidence of seroresistance was not significantly different among patients with different ages and genders, but was significantly different among patients with different disease courses, antibody titers, and medications. Patients with a baseline serum rapid plasma reagin (RPR) titer of greater than 1 8, a latent course, or a macrolide therapy history had higher incidences of seroresistance (i. e., 61%, 45.6%, and 72.7% respectively) than those who had a lower RPR titer, a primary course, or a benzathine penicillin therapy history.</p><p><b>CONCLUSION</b>Syphilis patients with a high baseline RPR titer, a latent course, and a macrolides therapy are prone to be seroresistant.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Reagins
/
Blood
/
Syphilis Serodiagnosis
/
Syphilis
/
Macrolides
/
Therapeutic Uses
/
Diagnosis
/
Drug Therapy
/
Allergy and Immunology
/
Methods
Type of study:
Diagnostic study
/
Incidence study
Limits:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Acta Academiae Medicinae Sinicae
Year:
2008
Type:
Article
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